Kaempferol
IUPAC name: 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
CAS Number: 520-18-3
Class: Flavonoid
Mushrooms contain this compound
8 mushrooms
| MushID |
Thai name |
Common name |
Scientific name |
Family |
| 1 |
เห็ดหลินจือ |
Lingzhi |
Ganoderma lucidum ( Curtis ) P. Karst. |
Ganodermataceae |
| 13 |
เห็ดหอม |
shiitake |
Lentinus edodes (Berk.) Sing. |
Marasmiaceae |
| 18 |
เห็ดโคนปลวกจิก |
- |
Termitomyces clypeatus Heim. |
Lyophyllaceae |
| 25 |
เห็ดขอนขาว |
- |
Lentinus squarrosulus Mont. |
Polyporaceae |
| 34 |
เห็ดลม |
flower mushrooms |
Lentinus polychrous Lév. |
Polyporaceae |
| 37 |
เห็ดหล่มขาว |
milk-white russula |
Russula delica Fr. |
Russulaceae |
| 40 |
เห็ดถ่านเล็ก |
crowded russula |
Russula densifolia Secr. ex Gillet |
Russulaceae |
| 45 |
เห็ดระโงกขาว |
- |
Amanita princeps Corner & Bas. |
Amanitaceae |
2D Structure
Compound Properties
SMILES
Oc1ccc(cc1)c1oc2cc(O)cc(c2c(=O)c1O)O
Physicochemical Properties
| Formula |
C15H10O6 |
| Molecular wieght(g/mol) |
286.24 |
| Num. of Heavy atoms |
21 |
| Num. of Aromatic Heavy atoms |
16 |
| Fraction Csp3 |
0.00 |
| Num. of Rotatable bonds |
1 |
| Num. of H-bond acceptors |
6 |
| Num. of H-bonds donors |
4 |
| Molar Refractivity |
76.01 |
| TPSA (square Angstrom) |
111.13 |
Lipophilicity
| iLOGP |
1.70 |
| XLOGP3 |
1.90 |
| WLOGP |
2.28 |
| MLOGP |
-0.03 |
| Silicos-IT LOGP |
2.03 |
| Consensus LOGP |
1.58 |
Water Solubility
| ESOL |
|
| LogS |
-3.31 |
Solubility(mg/ml) |
1.40E-01 |
Solubility(mol/l) |
4.90E-04 |
Class |
Soluble |
| Ali |
|
| LogS |
-3.86 |
Solubility(mg/ml) |
3.98E-02 |
Solubility(mol/l) |
1.39E-04 |
Class |
Soluble |
| Silicos-IT |
|
| LogS |
-3.82 |
Solubility(mg/ml) |
4.29E-02 |
Solubility(mol/l) |
1.50E-04 |
Class |
Soluble |
Pharmacokinetics
| GI absorbtion |
High |
| BBB permeant |
No |
| Pgp substrate |
No |
| CYP1A2 inhibitor |
Yes |
| CYP2C19 inhibitor |
No |
| CYP2C9 inhibitor |
No |
| CYP2D6 inhibitor |
Yes |
| CYP3A4 inhibitor |
Yes |
| Log Kp (skin permeation) (cm/s) |
-6.70 |
Druglikeness
| Lipinski Num. violations |
0 |
| Ghose Num. violations |
0 |
| Veber Num. violations |
0 |
| Egan Num. violations |
0 |
| Muegge Num. violations |
0 |
| Bioavailability Score |
0.55 |
Medicinal Chemistry
| PAINS Num. of alerts |
0 |
| Brenk Num. of alerts |
0 |
| Leadlikeness Num. of violations |
0 |
| Synthetic Accessibility |
3.14 |
Biological Activity
| Biological Activity |
JID |
| Antioxidant |
10 |
| Antioxidant |
19 |
