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3D MOLECULAR STRUCTURAL DATABASE OF BIOACTIVE COMPOUNDS FROM
MUSHROOMS
IN THAILAND
ADVANCE SEARCH
Mushroom Search
Mushroom Thai name
Mushroom common name
Mushroom scientific name
Family
Location
AND
OR
Chemical Search
Structure name
CAS No.
Formula
Class
AND
OR
Biological activity Search
Physicochemical properties
Molecular weight(g/mol)
To
Num. Heavy atom
Less than
Num. Aromatic atom
Less than
Num. Rotatable bond
Less than
Num. H-bond acceptor
Less than
Num. H-bond donor
Less than
TPSA(Angstrom)
To
Log P
To
Water Solubility Class
Insoluble
Poorly soluble
Moderately soluble
Soluble
Very soluble
Highly soluble
----
AND
OR
Pharmacokinetics
GI absorption
----
High
Low
BBB permeant
----
Yes
No
Pgp substrate
----
Yes
No
CYP inhibitor
----
Yes
No
Log Kp (skin permeation) (cm/s)
To
AND
OR
Druglikeness
Lipinski Num. violations
Ghose Num. violations
Veber Num. violations
Egan Num. violations
Muegge Num. violations
Bioavailability Score
----
0.11
0.17
0.55
0.56
0.85
AND
OR
Medicinal Chemistry
PAINS Num. of alerts
Brenk Num. of alerts
Leadlikeness Num. of violations
Synthetic Accessibility
Less than
AND
OR